In absence of protective buffers, prolonged exposure to excessive, early adversity can lead to poor health outcomes with significant impact lasting beyond the childhood years. Pregnancy and early childhood pose unique sensitivity to stressors such as economic instability, poor mental health, and social inequities all of which have been magnified by the COVID-19 pandemic. Chan School of Public Health, Boston, MA, United States 7Department of Nutrition, Harvard T.H.6Kraft Center for Community Health, Massachusetts General Hospital, Boston, MA, United States.5Center for Community Health Improvement, Massachusetts General Hospital, Boston, MA, United States.4MGH Revere HealthCare Center, Revere, MA, United States.3MGH Chelsea HealthCare Center, Chelsea, MA, United States.2Harvard Medical School, Boston, MA, United States.1Division of General Pediatrics, Department of Pediatrics, Massachusetts General Hospital for Children, Boston, MA, United States.Kwete 1,4, Alexy Arauz Boudreau 1,3, Mary Lyons Hunter 3, Maria Yolanda Parra 3, William Lopez 1, Amy Izen 3,5, Sarah N. Meisui Liu 1,2, Fernanda Neri Mini 1, Carlos Torres 1,3, Gracia M.

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